Copyright@2011 University of South Carolina
Wang Research Group
Collaborators
Theo W. Dreher (Oregon State University)

Todd Emrick (University of Massachusetts)

Byeongdu Lee (Argonne National Laboratory)

Xiaodong Li (University of South Carolina)

Catherine Murphy (University of South Carolina)

Thomas P. Russell (University of Massachusetts)

Zhaohui Su (Chinese Academy of Sciences)

Lin Yang (Brookhaven National Laboratory)
Research Groups in Bionanoparticle Technology
John E. Johnson

Marianne Manchester

S. Mann

Jonathan Trent

Mark Young

Kenneth Dawson

Vincent Rotello

Dave Evans

Amy Blum

Alexander A. Balandin

Angela Belcher

James N. Culver

Trevor Douglas

M. G. Finn

Matt Francis

Karen Wooley

Bogdan Dragnea

Nicole Steinmetz


Important Websites for Bionanotechnolgoy

VIPER

Ferritin

All Virology

Pymol (molecular visualization system)

PDB files

Bionanoparticle Related Literatures
1.Allan, A. C., M. Lapidot, et al. (2001). "An early tobacco mosaic virus-induced oxidative burst in tobacco indicates extracellular perception of the virus coat protein." Plant Physiol 126(1): 97-108.

2.Argos, P., M. G. Rossmann, et al. (1977). "A four-helical super-secondary structure." Biochem. Biophys. Res. Commun. 75(1): 83-6.

3.Asia, H. and N. Watanabe (1976). "Electric birefringence in concentrated solutions of tobacco mosaic virus." Biopolymers 15: 383-392.

4.Balci, S., A. M. Bittner, et al. (2006). "Copper nanowires within the central channel of tobacco mosaic virus particles." Electrochimica Acta 51(28): 6251-6257.

5.Bhyravbhatla, B., S. J. Watowich, et al. (1998). "Refined atomic model of the four-layer aggregate of the tobacco mosaic virus coat protein at 2.4-A resolution." Biophys J 74: 604-615.

6.Butler, P. J. (1999). "Self-assembly of tobacco mosaic virus: the role of an intermediate aggregate in generating both specificity and speed." Philos Trans R Soc Lond B Biol Sci 354(1383): 537-50.

7.Butler, P. J. G. and G. P. Lomonossoff (1978). "Quantized incorporation of RNA during assembly of tobacco mosaic virus from protein disks." J. Mol. Biol. 126(4): 877-82.

8.Butler, P. J. G. and G. P. Lomonossoff (1980). "RNA-protein interactions in the assembly of tobacco mosaic virus." Biophys. J. 32(1): 295-312.

9.Carr, J. P., L. E. Marsh, et al. (1992). "Resistance to tobacco mosaic virus induced by the 54-kDa gene sequence requires expression of the 54-kDa protein." Mol. Plant-Microbe Interact. 5(5): 397-404.

10.Chandrasekar, V. and J. E. Johnson (1998). "The structure of tobacco ringspot virus: a link in the evolution of icosahedral capsids in the picornavirus superfamily." Structure (London) 6(2): 157-171.

11.Chandrasekar, V., S. Munshi, et al. (1997). "Crystallization and preliminary X-ray analysis of tobacco ringspot virus." Acta Crystallogr., Sect. D: Biol. Crystallogr. D53(1): 125-128.

12.Coutts, R. H. A., J. E. Rigden, et al. (1991). "The complete nucleotide sequence of tobacco necrosis virus strain D." J. Gen. Virol. 72(7): 1521-9.

13.Culver, J. N. (1996). "Tobamovirus cross protection using a potexvirus vector." Virology 226(2): 228-35.

14.Culver, J. N. (2002). "Tobacco mosaic virus assembly and disassembly: determinants in pathogenicity and resistance." Annu Rev Phytopathol 40: 287-308.

15.Culver, J. N. and W. O. Dawson (1989). "Tobacco mosaic virus coat protein: an elicitor of the hypersensitive reaction but not required for the development of mosaic symptoms in Nicotiana sylvestris." Virology 173(2): 755-8.

16.Culver, J. N., W. O. Dawson, et al. (1995). "Site-directed mutagenesis confirms the involvement of carboxylate groups in the disassembly of tobacco mosaic virus." Virology 206(1): 724-30.

17.Culver, J. N., K. Lehto, et al. (1993). "Genomic position affects the expression of tobacco mosaic virus movement and coat protein genes." Proc Natl Acad Sci U S A 90(5): 2055-9.

18.Culver, J. N., G. Stubbs, et al. (1994). "Structure-function relationship between tobacco mosaic virus coat protein and hypersensitivity in Nicotiana sylvestris." J Mol Biol 242(2): 130-8.

19.Dardick, C. D., S. Golem, et al. (2000). "Susceptibility and symptom development in Arabidopsis thaliana to Tobacco mosaic virus is influenced by virus cell-to-cell movement." Mol Plant Microbe Interact 13(10): 1139-44.

20.Dickert, F. L., O. Hayden, et al. (2004). "Bioimprinted QCM sensors for virus detection-screening of plant sap." Anal Bioanal Chem 378(8): 1929-34.

21.Domier, L. L., K. M. Franklin, et al. (1986). "The nucleotide sequence of tobacco vein mottling virus RNA." Nucleic Acids Res. 14(13): 5417-30.

22.dos Reis Figueira, A., S. Golem, et al. (2002). "A nuclear localization signal and a membrane association domain contribute to the cellular localization of the Tobacco mosaic virus 126-kDa replicase protein." Virology 301(1): 81-9.

23.Douglas, T. and M. Young (1999). "Virus particles as templates for materials synthesis." Advanced Materials 11(8): 679-681.

24.Dubrovin, E. V., M. N. Kirikova, et al. (2004). "Study of peculiarities of adhesion of tobacco mosaic virus by atomic force microscopy." Colloid J. 66: 750-755.

25.Dujardin, E., C. Peet, et al. (2003). "Organization of Metallic Nanoparticles Using Tobacco Mosaic Virus Templates." Nano Letters 3(3): 413-417.

26.Flynn, C. E., S.-W. Lee, et al. (2003). "Viruses as vehicles for growth, organization and assembly of materials." Acta Materialia 51(19): 5867-5880.

27.Fonoberov, V. A. and A. A. Balandin (2005). "Phonon confinement effects in hybrid virus-inorganic nanotubes for nanoelectronic applications." Nano Lett 5(10): 1920-3.

28.Fowler, C. E., W. Shenton, et al. (2001). "Tobacco mosaic virus liquid crystals as templates for the interior design of silica mesophases and nanoparticles." Advanced Materials 13(16): 1266-1269.

29.Fraenkel-Conrat, H. (1955). "Reconstitution of active tobacco mosaic virus from its inactive protein and nucleic acid components." Proc Natl Acad Sci U S A 41: 690-698.

30.Ginoza, W. and D. E. Atkinson (1955). "Comparison of some physical and chemical properties of eight strains of tobacco mosaic virus." Virology 1(3): 253-60.

31.Goelet, P., G. P. Lomonossoff, et al. (1982). "Nucleotide sequence of tobacco mosaic virus RNA." Proc. Natl. Acad. Sci. U. S. A. 79(19): 5818-22.

32.Golem, S. and J. N. Culver (2003). "Tobacco mosaic virus induced alterations in the gene expression profile of Arabidopsis thaliana." Mol Plant Microbe Interact 16(8): 681-8.

33.Golemboski, D. B., G. P. Lomonossoff, et al. (1990). "Plants transformed with a tobacco mosaic virus nonstructural gene sequence are resistant to the virus." Proc. Natl. Acad. Sci. U. S. A. 87(16): 6311-15.

34.Goregaoker, S. P. and J. N. Culver (2003). "Oligomerization and activity of the helicase domain of the tobacco mosaic virus 126- and 183-kilodalton replicase proteins." J Virol 77(6): 3549-56.

35.Goregaoker, S. P., L. G. Eckhardt, et al. (2000). "Tobacco mosaic virus replicase-mediated cross-protection: contributions of RNA and protein-derived mechanisms." Virology 273(2): 267-75.

36.Goregaoker, S. P., D. J. Lewandowski, et al. (2001). "Identification and functional analysis of an interaction between domains of the 126/183-kDa replicase-associated proteins of tobacco mosaic virus." Virology 282(2): 320-8.

37.Goulden, M. G., J. W. Davies, et al. (1992). "Structure of tobraviral particles: A model suggested from sequence conservation in tobraviral and tobamoviral coat proteins." J. Mol. Biol. 227(1): 1-8.

38.Goulden, M. G., G. P. Lomonossoff, et al. (1991). "A model for the generation of tobacco rattle virus (TRV) anomalous isolates: pea early browning virus RNA-2 acquires TRV sequences from both RNA-1 and RNA-2." J. Gen. Virol. 72(7): 1751-4.

39.Jeng, T. W., R. A. Crowther, et al. (1989). "Visualization of alpha-helices in tobacco mosaic virus by cryo-electron microscopy." J Mol Biol 205(1): 251-7.

40.Kalinin, S. V., S. Jesse, et al. (2006). "Evidence for possible flexoelectricity in tobacco mosaic viruses used as nanotemplates." Applied Physics Letters 88(15).

41.Klug, A. (1999). "The tobacco mosaic virus particle: structure and assembly." Philos Trans R Soc Lond B Biol Sci 354(1383): 531-5.

42.Knez, M., A. Kadri, et al. (2006). "Atomic layer deposition on biological macromolecules: Metal oxide coating of tobacco mosaic virus and ferritin." Nano Letters 6(6): 1172-1177.

43.Knez, M., M. Sumser, et al. (2004). "Spatially selective nucleation of metal clusters on the tobacco mosaic virus." Adv. Funct. Mater. 14: 116-124.

44.Knez, M., M. P. Sumser, et al. (2004). "Binding the tobacco mosaic virus to inorganic surfaces." Langmuir 20(2): 441-7.

45.Larson, S. B., J. Day, et al. (1998). "Refined structure of satellite tobacco mosaic virus at 1.8 A resolution." J Mol Biol 277(1): 37-59.

46.Lee, S. Y., J. W. Choi, et al. (2006). "Deposition of platinum clusters on surface-modified tobacco mosaic virus." Journal of Nanoscience and Nanotechnology 6(4): 974-981.

47.Lee, S. Y., J. N. Culver, et al. (2006). "Effect of CuCl(2) concentration on the aggregation and mineralization of Tobacco mosaic virus biotemplate." J Colloid Interface Sci 297(2): 554-60.

48.Lewis, J. K., M. Bendahmane, et al. (1998). "Identification of viral mutants by mass spectrometry." Proc Natl Acad Sci U S A 95(15): 8596-601.

49.Lomonossoff, G. and J. E. Johnson (1995). "Eukaryotic viral expression systems for polypeptides." Semin. Virol. 6(4): 257-67.

50.Lomonossoff, G. P. (1993). "Virus resistance mediated by a nonstructural viral gene sequence." Transgenic Plants: 79-91.

51.Lomonossoff, G. P. and P. J. G. Butler (1979). "Location and encapsidation of the coat protein cistron of tobacco mosaic virus. A bidirectional elongation of the nucleoprotein rod." Eur. J. Biochem. 93(1): 157-64.

52.Lomonossoff, G. P. and P. J. G. Butler (1980). "Assembly of tobacco mosaic virus: elongation towards the 3 -hydroxyl terminus of the RNA." FEBS Lett. 113(2): 271-4.

53.Lomonossoff, G. P. and T. M. A. Wilson (1985). "Structure and in vitro assembly of tobacco mosaic virus." Mol. Plant Virol. 1: 43-83.

54.Lu, B., G. Stubbs, et al. (1996). "Carboxylate interactions involved in the disassembly of tobacco mosaic tobamovirus." Virology 225(1): 11-20.

55.Lu, B., G. Stubbs, et al. (1998). "Coat protein interactions involved in tobacco mosaic tobamovirus cross-protection." Virology 248(2): 188-98.

56.Lu, B., F. Taraporewala, et al. (1998). "Intersubunit interactions allowing a carboxylate mutant coat protein to inhibit tobamovirus disassembly." Virology 244(1): 13-9.

57.Nedoluzhko, A. and T. Douglas (2001). "Ordered association of tobacco mosaic virus in the presence of divalent metal ions." J. Inorg. Biochem. 84: 233-240.

58.Nida, D. L., J. R. Anjos, et al. (1992). "Expression of cowpea mosaic virus coat protein precursor in transgenic tobacco plants." J. Gen. Virol. 73(1): 157-63.

59.Niu, Z., V. S. Kotakadi, et al. (2006). "Study and characterization of tobacco mosaic virus head-to-tail assembly assisted by aniline polymerization." Chem. Commun.: 3019-3021.

60.Padmanabhan, M. S., S. P. Goregaoker, et al. (2005). "Interaction of the tobacco mosaic virus replicase protein with the Aux/IAA protein PAP1/IAA26 is associated with disease development." J Virol 79(4): 2549-58.

61.Porta, C. and G. P. Lomonossoff (1998). "Scope for using plant viruses to present epitopes from animal pathogens." Rev. Med. Virol. 8(1): 25-41.

62.Rodriguez-Cerezo, E., K. Findlay, et al. (1997). "The coat and cylindrical inclusion proteins of a potyvirus are associated with connections between plant cells." Virology 236(2): 296-306.

63.Royston, E., S. Y. Lee, et al. (2006). "Characterization of silica-coated tobacco mosaic virus." J Colloid Interface Sci 298(2): 706 - 712.

64.Schlick, T. L., Z. Ding, et al. (2005). "Dual-surface modification of the tobacco mosaic virus." J Am Chem Soc 127(11): 3718-23.

65.Sehnke, P. C. and J. E. Johnson (1993). "Crystallization and preliminary x-ray characterization of tobacco streak virus and a proteolytically modified form of the capsid protein." Virology 196(1): 328-31.

66.Sehnke, P. C., A. M. Mason, et al. (1989). "A \"zinc-finger\"-type binding domain in tobacco streak virus coat protein." Virology 168(1): 48-56.

67.Shenton, W., T. Douglas, et al. (1999). "Inorganic-organic nanotube composites from template mineralization of tobacco mosaic virus." Advanced Materials 11(3): 253-256.

68.Slocik JM, N. R., Stone MO, Wright DW (2005). "Viral templates for gold nanoparticle synthesis." JOURNAL OF MATERIALS CHEMISTRY 15: 749-753.

69.Smith, M. L., J. A. Lindbo, et al. (2006). "Modified Tobacco mosaic virus particles as scaffolds for display of protein antigens for vaccine applications." Virology 348(2): 475-88.

70.Taraporewala, Z. F. and J. N. Culver (1996). "Identification of an elicitor active site within the three-dimensional structure of the tobacco mosaic tobamovirus coat protein." Plant Cell 8(2): 169-78.

71.Taylor, S., A. Massiah, et al. (1994). "Correlation between the activities of five ribosome-inactivating proteins in depurination of tobacco ribosomes and inhibition of tobacco mosaic virus infection." Plant J. 5(6): 827-35.

72.Toedt, J. M., E. H. Braswell, et al. (1999). "Biophysical characterization of a designed TMV coat protein mutant, R46G, that elicits a moderate hypersensitivity response in Nicotiana sylvestris." Protein Sci 8(2): 261-70.

73.Tseng, R. J., C. Tsai, et al. (2006). "Digital memory device based on tobacco mosaic virus conjugated with nanoparticles." Nature Nanotechnology 1: 72-77.

74.Wadu-Mesthrige, K., B. Pati, et al. (1996). "Disaggregation of Tobacco Mosaic Virus by Bovine Serum Albumin." Langmuir 12: 3511-3515.

75.Wilson, T. M. A., G. P. Lomonossoff, et al. (1981). "Dimethyl sulfoxide (DMSO) disassembles tobacco mosaic virus predominantly from the 5 -end of the viral RNA." J. Gen. Virol. 53(2): 225-34.

76.Yi, H., S. Nisar, et al. (2005). "Patterned assembly of genetically modified viral nanotemplates via nucleic acid hybridization." Nano Lett 5(10): 1931-6.

77.Zaitlin, M. (2000). "Tobacco Mosaic Virus." AAB Descriptions of Plant Viruses 370: 8.

78.Zaitlin, M., D. Golemboski, et al. (1991). Virus resistance in plants transformed with nonstructural sequences from a pathogenic virus. PCT Int. Appl. Wo, (Cornell Research Foundation, Inc., USA). 32 pp.

79.Zaitlin, M., D. Golemboski, et al. (1993). Induction of viral resistance in plants by transformation with a replicase gene. PCT Int. Appl. Wo, (Cornell Research Foundation, Inc., USA). 46 pp.
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